Pyrazinyl-Substituted Aminoazoles as Covalent Inhibitors of Thrombin: Synthesis, Structure, and Anticoagulant Properties
Imberg, L.; Siutkina, A. I.; Erbacher, C.; Schmidt, J.; Broekmans, D. F.; Ovsepyan, R. A.; Daniliuc, C. G.; Gonçalves de Oliveira, E.; Serafim, M. S. M.; O’Donoghue, A. J.; Pillaiyar, T.; Panteleev, M. A.; Poso, A.; Kalinina, S. A.; Bermúdez, M.; Nekipelov, K.; Bendas, G.; Karst, U.; Kalinin, D. V.*
ACS Pharmacology & Translational Science, 8, 2025, 146-172. DOI: 10.1021/acsptsci.4c00515

Total synthesis of (±)-auranthine confirmed its refined structure.
Reinker, M.; Kalinina, S. A.; Kalinin, D. V.*
RSC Advances, 2024, 14(3), 1649-1654. DOI: DOI: https://doi.org/10.1039/D3RA07483H

Functional-Group-Tolerant Pd-Catalyzed Carbonylative Negishi Coupling with Aryl Iodides
Kalinin, D.V.; Ulven T.
ACS J. Org. Chem. 2023, 88, 23, 16633–16638. DOI: https://doi.org/10.1021/acs.joc.3c00948

Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin.
Imberg, L.; Platte, S.; Erbacher, C.; Daniliuc, C.G.; Kalinina, S.A.; Dörner, W.; Poso, A.; Karst, U.; Kalinin, D.V.*
ACS Pharmacology & Translational Science, 5, 2022, 1318-1347. DOI: https://doi.org/10.1021/acsptsci.2c00204

Microscale Parallel Synthesis of Acylated Aminotriazoles Enabling the Development of Factor XIIa and Thrombin Inhibitors.
Platte, S., Korff, M., Imberg, L., Balicioglu, I., Erbacher, C., Will, J.M., Daniliuc, C.G. and Karst, U., Kalinin, D.V.*
ChemMedChem 2021, 16, 3672 – 3690. DOI: https://doi.org/10.1002/cmdc.202100431

Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action. 
Korff, M.; Imberg, L.; Will, J. M.; Buckreiss, N.; Kalinina, S. A.; Wenzel, B. M.; Kastner, G. A.; Daniliuc, C. G.; Barth, M.; Ovsepyan, R. A.; Butov, K. R.; Humpf, H. U.; Lehr, M.; Panteleev, M. A.; Poso, A.; Karst, U.; Steinmetzer, T.; Bendas, G.; Kalinin, D. V.*
J. Med. Chem. 2020, 63, 13159-13186. DOI: https://doi.org/10.1021/acs.jmedchem.0c01635